Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984791 | 0.92 | ALDH1A1 (0.44) | ALDH1A1GAAPKML3MBTL1HPGD | |
| SCHEMBL19984981 | 0.86 | CYP1A2 (0.40) | ALDH1A1GAAHPGDLMNASMN1; SMN2 | |
| SCHEMBL19974309 | 0.84 | LMNA (0.42) | ALDH1A1GAAL3MBTL1HPGDLMNA | |
| SCHEMBL19984798 | 0.83 | CTSA (0.47) | ALDH1A1GAAL3MBTL1HPGDLMNA | |
| SCHEMBL19984807 | 0.82 | TP53 (0.43) | ALDH1A1L3MBTL1HPGDLMNASMN1; SMN2 | |
| SCHEMBL19984799 | 0.78 | KMT2A (0.43) | ALDH1A1GAAL3MBTL1HPGDLMNA | |
| SCHEMBL19984790 | 0.76 | ALDH1A1 (0.41) | ALDH1A1GAAL3MBTL1HPGDLMNA | |
| SCHEMBL19984828 | 0.67 | TP53 (0.47) | ALDH1A1L3MBTL1HPGDLMNASMN1; SMN2 | |
| SCHEMBL19984821 | 0.66 | CTSA (0.46) | ALDH1A1L3MBTL1HPGDLMNAHTT | |
| SCHEMBL19984849 | 0.65 | CTSA (0.43) | ALDH1A1L3MBTL1HPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |