Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974309 | 0.92 | LMNA (0.42) | ALDH1A1L3MBTL1LMNASTAT3HPGD | |
| SCHEMBL19984799 | 0.88 | KMT2A (0.43) | ALDH1A1L3MBTL1LMNASTAT3HPGD | |
| SCHEMBL19984791 | 0.84 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HPGDKDM4EHSD17B10 | |
| SCHEMBL19984798 | 0.82 | CTSA (0.47) | ALDH1A1L3MBTL1LMNASTAT3HPGD | |
| SCHEMBL19984807 | 0.81 | TP53 (0.43) | ALDH1A1L3MBTL1LMNASTAT3HPGD | |
| SCHEMBL19984845 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1LMNAHPGDKDM4E | |
| SCHEMBL19984981 | 0.76 | CYP1A2 (0.40) | ALDH1A1LMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL19984851 | 0.72 | CTSS (0.43) | ALDH1A1L3MBTL1LMNAHPGDKDM4E | |
| SCHEMBL19984793 | 0.71 | KMT2A (0.41) | ALDH1A1L3MBTL1LMNASTAT3HPGD | |
| SCHEMBL19984825 | 0.69 | ADAMTS4 (0.57) | ALDH1A1L3MBTL1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |