Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128925 | 0.90 | ABCB11 (0.52) | TDP1CNR2GAAHPGDABCB11 | |
| SCHEMBL15617596 | 0.85 | ACP3 (0.58) | TDP1CNR2MEN1KMT2AABCB11 | |
| SCHEMBL1979065 | 0.84 | TSHR (0.44) | TDP1HPGDMEN1KMT2ATSHR | |
| SCHEMBL3941057 | 0.81 | ABCB11 (0.49) | KMT2AABCB11TSHRALDH1A1L3MBTL1 | |
| SCHEMBL18055503 | 0.81 | FNTA (0.59) | CNR2GAAHPGDMEN1KMT2A | |
| SCHEMBL4441804 | 0.79 | KMT2A (0.57) | TDP1CNR2GAAHPGDMEN1 | |
| SCHEMBL1349310 | 0.79 | GAA (0.55) | TDP1CNR2GAAHPGDMEN1 | |
| SCHEMBL4435855 | 0.78 | CNR2 (0.52) | TDP1CNR2GAAHPGDMEN1 | |
| SCHEMBL4058257 | 0.78 | IDO1 (0.50) | CNR2GAAMEN1KMT2ATSHR | |
| SCHEMBL15342382 | 0.78 | SLC2A1 (0.59) | TDP1CNR2GAAHPGDCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306986-B1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC (US) | 2018-03-21 | — | — | EP | disclosed |