Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985041 | 0.97 | ANO1 (0.38) | PRMT5WDR77ALDH1A1PSMB5HTT | |
| SCHEMBL19985047 | 0.94 | PIN1 (0.38) | FFAR1KMT2AMEN1ANO1 | |
| SCHEMBL19985045 | 0.86 | ALDH1A1 (0.39) | PRMT5WDR77ALDH1A1PSMB5HTT | |
| SCHEMBL19984881 | 0.83 | ANO1 (0.38) | PRMT5WDR77ALDH1A1PSMB5HTT | |
| SCHEMBL23934480 | 0.82 | PIN1 (0.43) | KMT2AMEN1TSHRANO1 | |
| SCHEMBL19984900 | 0.82 | FFAR1 (0.38) | FFAR1KMT2AMEN1CYP3A4 | |
| SCHEMBL21538694 | 0.81 | ALDH1A1 (0.43) | PRMT5WDR77ALDH1A1HTTXBP1 | |
| SCHEMBL19984893 | 0.80 | SIGMAR1 (0.32) | ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL23934559 | 0.80 | PIN1 (0.38) | ALDH1A1HTTXBP1FFAR1KMT2A | |
| SCHEMBL19984877 | 0.79 | TSHR (0.37) | ALDH1A1PSMB5KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050477-A1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |