Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984808 | 0.78 | EGFR (0.50) | PTK2ANO1ANO2PTGS2LMNA | |
| SCHEMBL19984828 | 0.77 | TP53 (0.47) | PTK2ANO1ANO2PTGS2LMNA | |
| SCHEMBL13073875 | 0.73 | PTK2 (0.59) | PTK2ANO1ANO2PTGS2LMNA | |
| SCHEMBL3828361 | 0.72 | PTK2 (0.57) | PTK2ANO1ANO2PTGS2LMNA | |
| SCHEMBL16509724 | 0.71 | ALDH1A1 (0.57) | PTK2ANO1ANO2PTGS2LMNA | |
| SCHEMBL1543450 | 0.70 | PTK2 (0.55) | PTK2ANO1ANO2PTGS2LMNA | |
| SCHEMBL19984996 | 0.69 | ANO1 (0.45) | PTK2ANO1ANO2PTGS2LMNA | |
| SCHEMBL19984784 | 0.69 | PTK2 (0.47) | PTK2ANO1ANO2PTGS2LMNA | |
| SCHEMBL19002358 | 0.67 | ANO1 (0.59) | PTK2ANO1ANO2LMNAL3MBTL1 | |
| SCHEMBL19984789 | 0.67 | APLNR (0.54) | LMNAL3MBTL1KMT2AHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |