Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 6/20 | 0.54 |
| ▸ | VDR | P11473 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984976 | 0.84 | APLNR (0.54) | APLNRKMT2APARP1HPGD | |
| SCHEMBL16495669 | 0.78 | WNT3A (0.46) | APLNRALOX15KMT2AMEN1GUSB | |
| SCHEMBL19984815 | 0.77 | KMT2A (0.48) | APLNRLMNATP53KMT2AHPGD | |
| SCHEMBL19984977 | 0.75 | APLNR (0.44) | APLNRKMT2APARP1HPGDSMN1; SMN2 | |
| SCHEMBL19984985 | 0.74 | ADAMTS4 (0.55) | APLNRPARP1HPGDHDAC1 | |
| SCHEMBL19984787 | 0.74 | VDR (0.46) | VDRALOX15KDM4ELMNATP53 | |
| SCHEMBL2437020 | 0.74 | CTSS (0.48) | APLNRVDRALOX15KDM4ELMNA | |
| SCHEMBL2440740 | 0.74 | HPGD (0.52) | APLNRALOX15KDM4ELMNATP53 | |
| SCHEMBL15595972 | 0.73 | SMN1; SMN2 (0.52) | KDM4ELMNAKMT2APOLBHTT | |
| SCHEMBL18276868 | 0.72 | APLNR (0.72) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |