Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | VDR | P11473 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089254 | 0.86 | VDR (0.61) | RAB9ATSHRMAPK1VDRMEN1 | |
| SCHEMBL6361819 | 0.83 | RAB9A (0.78) | RAB9ATSHRMAPK1MEN1KMT2A | |
| SCHEMBL8366844 | 0.82 | RAB9A (0.76) | RAB9ATSHRMAPK1MEN1KMT2A | |
| SCHEMBL8366932 | 0.82 | RAB9A (0.76) | RAB9ATSHRMAPK1MEN1KMT2A | |
| SCHEMBL7259937 | 0.81 | RAB9A (0.74) | RAB9ATSHRMAPK1MEN1KMT2A | |
| SCHEMBL9682433 | 0.77 | TBXA2R (0.77) | — | |
| SCHEMBL2900203 | 0.76 | MEN1 (0.66) | RAB9ATSHRMAPK1MEN1KMT2A | |
| SCHEMBL10443449 | 0.76 | RAB9A (0.66) | RAB9ATSHRMAPK1MEN1KMT2A | |
| SCHEMBL9681443 | 0.76 | TBXA2R (0.61) | TSHRMAPK1VDR | |
| SCHEMBL10443451 | 0.75 | RAB9A (0.64) | RAB9ATSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944310-B1 | MIF inhibitors for the acute or chronic treatment of pulmonary hypertension | MIFCARE (FR) | 2018-03-21 | — | — | EP | disclosed |