SCHEMBL19985566

SCHEMBL19985566

C=CCCC1CCC(c2ccc(-c3ccc(OCC)c(F)c3F)c(F)c2F)CC1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 2/20 0.32
CNR2 P34972 5/20 0.31
CNR1 P21554 2/20 0.31
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3911932 0.95 OPRL1 (0.32) CNR2CNR1OPRL1
SCHEMBL3911928 0.95 OPRL1 (0.32) CNR2CNR1OPRL1
SCHEMBL8935622 0.94 FPR2 (0.33) FPR2ALOX5APFEN1
SCHEMBL19985567 0.92 GABRA1 (0.35) FPR2CNR2ALOX5APFEN1
SCHEMBL17522424 0.92
SCHEMBL16676023 0.92 OPRL1 (0.31) OPRL1
SCHEMBL8963066 0.92 FPR2 (0.32) FPR2ALOX5APFEN1
SCHEMBL19985564 0.91 PTGES (0.33) FPR2CNR2CNR1ALOX5APFEN1
SCHEMBL22277549 0.91 OPRL1 (0.30) OPRL1
SCHEMBL22277444 0.91 OPRL1 (0.30) OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed