Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.39 |
| ▸ | HTR2A | P28223 | 9/20 | 0.39 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935065 | 0.94 | HTR2C (0.37) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL19985274 | 0.92 | HTR2C (0.40) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL8962246 | 0.91 | HTR2C (0.35) | HTR2CHTR2AHTR2BLMNAMEN1 | |
| SCHEMBL19985593 | 0.91 | HTR2C (0.38) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL19985603 | 0.89 | HTR2C (0.36) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL19985591 | 0.88 | FPR2 (0.32) | FPR2 | |
| SCHEMBL19985581 | 0.88 | HTR2C (0.39) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL19985605 | 0.88 | HTR2C (0.36) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL19985467 | 0.87 | FPR2 (0.36) | FPR2 | |
| SCHEMBL19985590 | 0.87 | HTR1A (0.31) | HTR1ACTSLCTSSCTSKFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |