Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985851 | 0.88 | FPR1 (0.45) | HTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL19985847 | 0.87 | DPP4 (0.45) | DPP4ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL19972328 | 0.86 | FPR1 (0.49) | DPP4HTTALDH1A1MEN1GAA | |
| SCHEMBL19972327 | 0.86 | FPR1 (0.49) | DPP4HTTALDH1A1MEN1GAA | |
| SCHEMBL19972331 | 0.86 | FPR1 (0.49) | DPP4HTTALDH1A1MEN1GAA | |
| SCHEMBL1243424 | 0.82 | DPP4 (0.71) | DPP4HTTALDH1A1MEN1GAA | |
| SCHEMBL1243419 | 0.82 | DPP4 (0.71) | DPP4HTTALDH1A1MEN1GAA | |
| SCHEMBL1243422 | 0.82 | DPP4 (0.71) | DPP4HTTALDH1A1MEN1GAA | |
| SCHEMBL19985859 | 0.81 | HPGD (0.51) | DPP4HTTALDH1A1KMT2AHPGD | |
| SCHEMBL19972390 | 0.80 | FPR1 (0.49) | HTTALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | DPP4 4385/4885HTT 3532/4885ALDH1A1 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.