Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 12/20 | 0.51 |
| ▸ | FPR2 | P25090 | 10/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20921423 | 0.86 | FPR1 (0.64) | FPR1FPR2KDM1AMAOBMAOA | |
| SCHEMBL19988733 | 0.86 | FPR1 (0.64) | FPR1FPR2KDM1AMAOBMAOA | |
| SCHEMBL19988652 | 0.85 | FPR1 (0.62) | FPR1FPR2KDM1AMAOBMAOA | |
| SCHEMBL19988379 | 0.85 | FPR1 (0.62) | FPR1FPR2KDM1AMAOBMAOA | |
| SCHEMBL19985862 | 0.82 | KDM1A (0.46) | FPR1FPR2KDM1AMAOBMAOA | |
| SCHEMBL24890670 | 0.82 | KDM1A (0.67) | KDM1AMAOBMAOAEPHX2NFKB1 | |
| SCHEMBL24890518 | 0.82 | KDM1A (0.67) | KDM1AMAOBMAOAEPHX2NFKB1 | |
| SCHEMBL24890671 | 0.82 | KDM1A (0.67) | KDM1AMAOBMAOAEPHX2NFKB1 | |
| SCHEMBL24890668 | 0.82 | KDM1A (0.67) | KDM1AMAOBMAOAEPHX2NFKB1 | |
| SCHEMBL19985857 | 0.81 | FPR1 (0.52) | FPR1FPR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | FPR1 2/4885FPR2 1/4885KDM1A 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.