SCHEMBL19986078

SCHEMBL19986078

c1ccc2c(c1)oc1cccc(-n3c4ccccc4c4c5c6ccccc6c6ccccc6c5c5c6ccccc6oc5c43)c12

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
PGAM1 P18669 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CDC14B O60729 1/20 0.32
CDC14A Q9UNH5 1/20 0.32
KDM5A P29375 1/20 0.31
AHR P35869 1/20 0.31
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986065 0.90 MEN1 (0.36) MAOAKDM5AAHR
SCHEMBL19986022 0.89 CNR1 (0.37) MAOAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL19986072 0.88 KDM4E (0.41) KDM4EALDH1A1SMN1; SMN2HSD17B10LMNA
SCHEMBL19986080 0.87 BRDT (0.32)
SCHEMBL19997973 0.86 KDM4E (0.41) KDM4EALDH1A1SMN1; SMN2HSD17B10LMNA
SCHEMBL22011533 0.85 MAOA (0.31) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL19986074 0.84 KDM4E (0.41) KDM4EALDH1A1SMN1; SMN2HSD17B10LMNA
SCHEMBL19986016 0.84 KDM4E (0.44) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL19985998 0.84 CDC14B (0.38) KDM4EMAPTCDC14BCDC14A
SCHEMBL19986073 0.83 ESR2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed