SCHEMBL22011533

SCHEMBL22011533

c1ccc2c(c1)oc1cccc(-n3c4ccccc4c4c5oc6ccccc6c5c5c(ccc6oc7ccccc7c65)c43)c12

nearest known ligand 0.31

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.31
SMN1; SMN2 Q16637 2/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
PGAM1 P18669 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CDC14B O60729 1/20 0.30
CDC14A Q9UNH5 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22011531 0.87 KDM4E (0.40) SMN1; SMN2KDM4EALDH1A1MAPTHPGD
SCHEMBL22011528 0.87 CDC14B (0.35) MAPTCDC14BCDC14A
SCHEMBL22011530 0.86 ALOX5 (0.32) CDC14BCDC14A
SCHEMBL19986078 0.85 MAOA (0.33) MAOASMN1; SMN2KDM4EALDH1A1GLA
SCHEMBL22011540 0.84 ALDH1A1 (0.32) SMN1; SMN2KDM4EALDH1A1MAPTHPGD
SCHEMBL22011534 0.82 WNK1 (0.34) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL22011535 0.81 MEN1 (0.33) KDM4EALDH1A1CYP3A4MAPTHPGD
SCHEMBL22011563 0.80 MAPT (0.36) KDM4EALDH1A1CYP3A4MAPTHPGD
SCHEMBL17246022 0.80 AHR (0.35) MAOASMN1; SMN2KDM4EALDH1A1GLA
SCHEMBL22011538 0.79 KDM4E (0.39) KDM4EALDH1A1HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
EP-3880682-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-14 EP disclosed
US-20220006030-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-01-06 US disclosed
WO-2020099307-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220006030-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES ZYX, RER1, AOC2 MAOA 1223/4885SMN1; SMN2 1351/4885KDM4E 1792/4885
US-12035625-B2 Materials for organic electroluminescent devices ZYX, RER1, AOC2 MAOA 1223/4885SMN1; SMN2 1351/4885KDM4E 1792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.