SCHEMBL19985998

SCHEMBL19985998

c1ccc(-c2ccccc2-n2c3ccccc3c3c4c5ccccc5c5ccccc5c4c4c5ccccc5oc4c32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC14B O60729 2/20 0.38
CDC14A Q9UNH5 2/20 0.38
CYP17A1 P05093 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
MEN1 O00255 1/20 0.33
CSF1R P07333 1/20 0.33
PDGFRB P09619 1/20 0.33
MAPT P10636 1/20 0.33
KIT P10721 1/20 0.33
FLT3 P36888 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX5 P09917 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17405336 0.89 KDM4E (0.40) CDC14BCDC14AMEN1MAPTKMT2A
SCHEMBL17405331 0.87 KDM4E (0.38) CDC14BCDC14AMEN1KMT2AKDM4E
SCHEMBL22011528 0.85 CDC14B (0.35) CDC14BCDC14ACYP17A1CYP19A1CYP11B1
SCHEMBL19997960 0.85 L3MBTL1 (0.41) MEN1MAPTKMT2AHDAC6KDM4E
SCHEMBL19986078 0.84 MAOA (0.33) CDC14BCDC14AMAPTKDM4E
SCHEMBL19986072 0.84 KDM4E (0.41) MEN1KMT2AKDM4EATML3MBTL1
SCHEMBL19986063 0.83 KDM4E (0.37) CDC14BCDC14AMEN1KMT2AKDM4E
SCHEMBL19986042 0.83 KDM4E (0.37) CDC14BCDC14AMEN1CSF1RPDGFRB
SCHEMBL19986007 0.83 KDM4E (0.37) CDC14BCDC14AMEN1CSF1RPDGFRB
SCHEMBL19986065 0.83 MEN1 (0.36) MEN1KMT2AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed