SCHEMBL22200008

SCHEMBL22200008

c1ccc(-c2ccc(-c3nc(-n4c5ccccc5c5c6ccccc6c6c7ccccc7oc6c54)nc4c3ccc3ccccc34)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.33
MEN1 O00255 1/20 0.33
CSF1R P07333 1/20 0.33
PDGFRB P09619 1/20 0.33
KIT P10721 1/20 0.33
FLT3 P36888 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTGER1 P34995 1/20 0.32
ALDH1A1 P00352 2/20 0.30
HPGD P15428 2/20 0.30
TSHR P16473 1/20 0.30
KDM4E B2RXH2 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18132431 0.98 MAPT (0.34) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL19986143 0.94 MEN1 (0.32) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL18132444 0.92 PRKDC (0.31) MAPTALDH1A1
SCHEMBL19986142 0.92 MAPT (0.33) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL22200027 0.91 TDP1 (0.31) TDP1L3MBTL1
SCHEMBL19428432 0.91 MAPT (0.34) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL24171787 0.90 MEN1 (0.32) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL19546286 0.90 MAPT (0.33) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL18132436 0.90 PTGER1 (0.31) L3MBTL1PTGER1KDM4E
SCHEMBL19428427 0.89 MAPT (0.35) MAPTMEN1CSF1RPDGFRBKIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERF2, PIEZO1, TERT MAPT 2914/4885MEN1 1732/4885CSF1R 2919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.