Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.57 |
| ▸ | CCR8 | P51685 | 3/20 | 0.57 |
| ▸ | CCR5 | P51681 | 2/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.57 |
| ▸ | TOP1 | P11387 | 6/20 | 0.54 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437210 | 0.85 | CCR1 (0.53) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL18434453 | 0.85 | L3MBTL1 (0.57) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL28484814 | 0.83 | COMT (0.46) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL7440046 | 0.83 | PDE4A (0.54) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL7437244 | 0.80 | CCR1 (0.50) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL7449668 | 0.79 | PDE4A (0.51) | CCR1CCR8CCR5PSMD14COPS5 | |
| SCHEMBL18434758 | 0.79 | KDM4E (0.56) | CCR1CCR8CCR5TOP1PDE4A | |
| SCHEMBL7448426 | 0.79 | PDE4A (0.56) | CCR1CCR8TOP1PDE4APDE4B | |
| SCHEMBL31086216 | 0.79 | TOP1 (0.59) | TOP1PDE4ASLC40A1KDM4EHSP90AA1 | |
| SCHEMBL9825204 | 0.78 | KDM4E (0.52) | CCR1CCR8CCR5TOP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530173-A | Palladium-catalyzed quinoline and method for selectively arylating C (8) -H bond of derivative thereof | 洛阳理工学院 | 2024-08-23 | — | — | CN | disclosed |
| US-10826000-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-11-03 | — | — | US | disclosed |
| US-20190036043-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-01-31 | — | — | US | disclosed |
| US-20160111664-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-04-21 | — | — | US | disclosed |
| EP-0691966-B1 | QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS | SYNTEX INC (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0691966-A1 | QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5455252-A | Antiinflammatory agent, immunosuppressant, antiallergen, skin disorders, bronchodilator, analgesic | SYNTEX (U.S.A.) INC. (US) | 1995-10-03 | — | — | US | disclosed |
| WO-1994022852-A1 | QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1994-10-13 | — | — | WO | disclosed |