Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26692444 | 0.77 | — | — | |
| SCHEMBL24329784 | 0.75 | — | — | |
| SCHEMBL22555800 | 0.72 | — | — | |
| SCHEMBL18114605 | 0.71 | — | — | |
| SCHEMBL21630299 | 0.71 | — | — | |
| SCHEMBL5777184 | 0.71 | — | — | |
| SCHEMBL21630274 | 0.71 | — | — | |
| SCHEMBL4760870 | 0.71 | — | — | |
| SCHEMBL9497786 | 0.71 | — | — | |
| SCHEMBL2051187 | 0.69 | TRHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10568326-B2 | 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-25 | — | — | US | disclosed |
| US-10568326-B2 | 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-25 | — | — | US | disclosed |
| US-20200039973-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-06 | — | — | US | disclosed |
| US-20200039973-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-06 | — | — | US | disclosed |
| US-20200029564-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLOXIRANE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20200029564-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLOXIRANE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20200031778-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20200031778-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20190223437-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A 5-SUBSTITUTED IMIDAZOLE DERIVATIVE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-25 | — | — | US | disclosed |
| US-20190223437-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A 5-SUBSTITUTED IMIDAZOLE DERIVATIVE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-25 | — | — | US | disclosed |
| US-10231453-B2 | 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-03-19 | — | — | US | disclosed |
| US-10231453-B2 | 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-03-19 | — | — | US | disclosed |
| WO-2018060074-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |
| WO-2018060091-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |
| WO-2018060090-A1 | 5-SUBSTITUTED IMIDAZOLYLMETHYLOXIRANE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |
| WO-2018060093-A1 | 1,5-SUBSTITUTED IMIDAZOLE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION. | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |
| US-20180084780-A1 | Novel 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | US | disclosed |
| US-20180084780-A1 | Novel 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | US | disclosed |
| US-20180084780-A1 | Novel 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | US | disclosed |
| WO-2018050456-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A 5-SUBSTITUTED IMIDAZOLE DERIVATIVE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180084780-A1 | Novel 5-substituted imidazole derivatives | MYB, IRF3, PIP5K1B | KDM4E 429/4885HPGD 2190/4885MEN1 3969/4885 |
| US-10231453-B2 | 5-substituted imidazole derivatives | MYB, PIKFYVE, PIP5K1B | KDM4E 392/4885HPGD 1948/4885MEN1 3794/4885 |
| US-20200039973-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | IPMK, PIP5K1B, PIP5K1C | KDM4E 608/4885HPGD 2995/4885MEN1 3947/4885 |
| US-20200031778-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | IPMK, PIP5K1B, PIP5K1C | KDM4E 608/4885HPGD 2995/4885MEN1 3947/4885 |
| US-20200029564-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLOXIRANE DERIVATIVES | PIP5K1B, IPMK, IPO5 | KDM4E 450/4885HPGD 791/4885MEN1 3706/4885 |
| US-10568326-B2 | 5-substituted imidazole derivatives | MYB, PIKFYVE, PIP5K1B | KDM4E 392/4885HPGD 1948/4885MEN1 3794/4885 |
| US-20190223437-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A 5-SUBSTITUTED IMIDAZOLE DERIVATIVE | ERG28, API5, CASP5 | KDM4E 459/4885HPGD 3311/4885MEN1 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.