Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585046 | 0.79 | MAPT (0.35) | MAPTGAAKMT2AP2RX7 | |
| SCHEMBL19986448 | 0.74 | MAPT (0.40) | MAPTGAAITGB1ITGA4KDM4E | |
| SCHEMBL28579955 | 0.72 | MAPT (0.31) | MAPTP2RX7 | |
| SCHEMBL19986641 | 0.71 | STK17A (0.37) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL8923850 | 0.66 | MAPT (0.50) | MAPTGAAITGB1ITGA4KDM4E | |
| SCHEMBL26049474 | 0.65 | RXFP1 (0.35) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL19986703 | 0.64 | MAPT (0.38) | MAPTGAAITGB1ITGA4KDM4E | |
| SCHEMBL28577567 | 0.63 | HTR2A (0.33) | MAPTHRH4HRH3 | |
| SCHEMBL28622324 | 0.62 | MAPT (0.31) | MAPT | |
| SCHEMBL1665457 | 0.62 | MAPT (0.42) | MAPTGAAKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |