SCHEMBL26049474

SCHEMBL26049474

CC(CN)CNc1c(N)nc[nH]c1=O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.35
ALDH1A1 P00352 3/20 0.31
KDM4E B2RXH2 2/20 0.31
GAA P10253 2/20 0.31
LMNA P02545 2/20 0.31
GLA P06280 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 3/20 0.31
TMIGD3 P0DMS9 1/20 0.31
CYP2C9 P11712 1/20 0.31
ADORA1 P30542 1/20 0.31
GDA Q9Y2T3 1/20 0.30
CPB1 P15086 1/20 0.30
CPB2 Q96IY4 1/20 0.30
CYP2C19 P33261 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26049344 0.92 RXFP1 (0.37) RXFP1ALDH1A1KDM4EGAALMNA
SCHEMBL9667342 0.72 XDH (0.49) ALDH1A1KDM4EGAALMNAMEN1
SCHEMBL11901381 0.67 GDA (0.44) RXFP1ALDH1A1KDM4EGAAGLA
SCHEMBL15281154 0.65 ADORA2A (0.36) ALDH1A1KDM4EGAAGLACYP1A2
SCHEMBL19986470 0.65 MAPT (0.38) ALDH1A1KDM4EGAAGLAMEN1
SCHEMBL9669058 0.65 CYP2C19 (0.43) ALDH1A1KDM4EADORA1GDACYP2C19
SCHEMBL11678138 0.65 PNP (0.35) ALDH1A1CYP1A2CYP2D6
SCHEMBL17845811 0.63 NPC1 (0.40) MEN1KMT2ACYP1A2CYP2C19
SCHEMBL9667337 0.63 XDH (0.50) ALDH1A1KDM4ELMNAGLA
SCHEMBL26049473 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023150684-A2 NANOMATERIAL AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2023-08-10 WO disclosed