SCHEMBL28622324

SCHEMBL28622324

CC1OC1(CN)CNc1c(Cl)cncc1Cl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986728 0.74
SCHEMBL28571392 0.72 P2RX7 (0.32)
SCHEMBL28577549 0.72 CCNT1 (0.30)
SCHEMBL28576952 0.71 P2RX7 (0.34)
SCHEMBL19986641 0.65 STK17A (0.37) MAPT
SCHEMBL19986524 0.65 P2RX7 (0.33) MAPT
SCHEMBL19986470 0.62 MAPT (0.38) MAPT
SCHEMBL28585046 0.59 MAPT (0.35) MAPT
SCHEMBL6221844 0.59 P2RX7 (0.43)
SCHEMBL19986448 0.58 MAPT (0.40) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429341-A Novel capsid protein assembly inhibitors 正大天晴药业集团股份有限公司 2021-09-24 CN disclosed