Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986651 | 0.93 | KDM4E (0.43) | KDM4EKMT2ASMN1; SMN2MEN1ROCK2 | |
| SCHEMBL19986554 | 0.80 | MEN1 (0.47) | RECQLKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL19986515 | 0.77 | KCNQ3 (0.47) | KMT2ASMN1; SMN2MEN1POLBHDAC1 | |
| SCHEMBL19986564 | 0.75 | NAMPT (0.52) | RECQLKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12753428 | 0.74 | HDAC1 (0.49) | KMT2AMEN1ALDH1A1POLBIDO1 | |
| SCHEMBL19986446 | 0.72 | KMT2A (0.49) | KDM4EKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL15631001 | 0.72 | KDM4E (0.51) | KDM4EKMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL19986507 | 0.72 | KMT2A (0.38) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL15006963 | 0.71 | HDAC1 (0.51) | KDM4ERECQLALDH1A1POLBIDO1 | |
| SCHEMBL22231457 | 0.71 | CA12 (0.51) | KMT2AMEN1ALDH1A1POLBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |