Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986446 | 0.88 | KMT2A (0.49) | KMT2AMEN1NAMPTTP53KDM4E | |
| SCHEMBL19986564 | 0.88 | NAMPT (0.52) | KMT2AMEN1NAMPTALDH1A1EPHX2 | |
| SCHEMBL19986554 | 0.85 | MEN1 (0.47) | KMT2AMEN1NAMPTFLT4SLC6A3 | |
| SCHEMBL19986506 | 0.85 | MEN1 (0.43) | KMT2AMEN1NAMPTTP53KDM4E | |
| SCHEMBL19986699 | 0.81 | LMNA (0.53) | KMT2AMEN1NAMPTTP53CYP1A2 | |
| SCHEMBL19986718 | 0.79 | ALDH1A1 (0.42) | KMT2AMEN1CDK2FLT4KDM4E | |
| SCHEMBL19986631 | 0.79 | KMT2A (0.53) | KMT2AMEN1NAMPTTP53ALDH1A1 | |
| SCHEMBL19986708 | 0.78 | KDM4E (0.39) | KMT2AMEN1NAMPTCDK2FLT4 | |
| SCHEMBL19986578 | 0.78 | MEN1 (0.41) | KMT2AMEN1NAMPTCDK2FLT4 | |
| SCHEMBL19986671 | 0.74 | EPHX2 (0.49) | KMT2AMEN1TP53KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |