Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986564 | 0.93 | NAMPT (0.52) | MEN1KMT2ANAMPTALDH1A1LMNA | |
| SCHEMBL19986446 | 0.90 | KMT2A (0.49) | MEN1KMT2ANAMPTSLC6A3ALDH1A1 | |
| SCHEMBL19986507 | 0.85 | KMT2A (0.38) | MEN1KMT2ANAMPTSLC6A3ALDH1A1 | |
| SCHEMBL19986699 | 0.84 | LMNA (0.53) | MEN1KMT2ANAMPTMAPTLMNA | |
| SCHEMBL19986631 | 0.81 | KMT2A (0.53) | MEN1KMT2ANAMPTALDH1A1MAPT | |
| SCHEMBL19986607 | 0.80 | NAMPT (0.41) | MEN1KMT2ABLMNAMPTKDR | |
| SCHEMBL19986694 | 0.80 | NAMPT (0.41) | MEN1KMT2ABLMNAMPTKDR | |
| SCHEMBL19986509 | 0.80 | BLM (0.43) | MEN1KMT2ABLMNAMPTKDR | |
| SCHEMBL19986683 | 0.80 | KDR (0.38) | BLMNAMPTKDRMAPTGRM4 | |
| SCHEMBL19986516 | 0.80 | KDM4E (0.43) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |