Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 3/20 | 0.42 |
| ▸ | CDK1 | P06493 | 3/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986738 | 0.92 | SLC2A1 (0.46) | SLC2A1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL19970728 | 0.78 | FAAH (0.63) | SLC2A1AURKACDK1CCNB1CDK2 | |
| SCHEMBL19970873 | 0.77 | FAAH (0.61) | AURKACDK1CCNB1CDK2AURKB | |
| SCHEMBL19970828 | 0.74 | NPBWR1 (0.64) | SLC2A1BCHEACHEHDAC6HDAC3 | |
| SCHEMBL19970835 | 0.73 | BCHE (0.53) | SLC2A1BCHEACHEHDAC6HDAC3 | |
| SCHEMBL19970807 | 0.72 | ACACB (0.62) | SLC2A1BCHEACHEHDAC6HDAC3 | |
| SCHEMBL19970727 | 0.72 | FAAH (0.63) | SLC2A1FAAH | |
| SCHEMBL19970741 | 0.71 | RUNX1 (0.61) | SLC2A1BCHEACHEHTR1ADRD2 | |
| SCHEMBL19970777 | 0.71 | SLC2A1 (0.58) | SLC2A1BCHEACHEHDAC6HDAC3 | |
| SCHEMBL19970830 | 0.70 | FAAH (0.56) | SLC2A1AURKACDK1CCNB1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |