Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 7/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986732 | 0.92 | SLC2A1 (0.48) | SLC2A1AURKACDK1CCNB1CDK2 | |
| SCHEMBL19970830 | 0.80 | FAAH (0.56) | SLC2A1ALDH1A1HPGDHSD17B10AURKA | |
| SCHEMBL19970868 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10AURKACDK1 | |
| SCHEMBL19970798 | 0.76 | KCNH2 (0.62) | SLC2A1ALDH1A1HPGDAURKACDK1 | |
| SCHEMBL19970737 | 0.74 | SLC2A1 (0.57) | SLC2A1KITHDAC3HDAC1HDAC2 | |
| SCHEMBL19970829 | 0.74 | FAAH (0.56) | SLC2A1KITFAAH | |
| SCHEMBL19970730 | 0.74 | RUNX1 (0.54) | SLC2A1ALDH1A1HPGDAURKACDK1 | |
| SCHEMBL19970764 | 0.74 | AURKA (0.47) | SLC2A1ALDH1A1HPGDHSD17B10AURKA | |
| SCHEMBL19970867 | 0.73 | FAAH (0.54) | ALDH1A1HPGDHSD17B10KITFAAH | |
| SCHEMBL19970841 | 0.72 | RUNX1 (0.53) | SLC2A1ALDH1A1HPGDAURKACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |