SCHEMBL1998702

SCHEMBL1998702

O=C(O)c1ccccc1-c1c2nc(cc3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.56
▸ STAT1 P42224 1/20 0.56
▸ KDM4E B2RXH2 2/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ POLB P06746 1/20 0.41
▸ TOP1 P11387 3/20 0.39
▸ CYCS P99999 3/20 0.38
▸ MYC P01106 1/20 0.37
▸ SOS1 Q07889 1/20 0.36
▸ DHODH Q02127 5/20 0.36
▸ ADORA2B P29275 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29062206 0.99 STAT3 (0.55) STAT3STAT1KDM4ERAB9APOLB
SCHEMBL30583773 0.99 STAT3 (0.55) STAT3STAT1KDM4ERAB9APOLB
SCHEMBL30583769 0.95 STAT3 (0.53) STAT3STAT1KDM4ERAB9APOLB
SCHEMBL30583768 0.94 STAT3 (0.55) STAT3STAT1KDM4ERAB9APOLB
SCHEMBL4410598 0.86 STAT3 (0.49) STAT3STAT1KDM4E
SCHEMBL1535116 0.84 STAT3 (0.48) STAT3STAT1TOP1CYCSDHODH
SCHEMBL455572 0.83 KDM4E (0.47) STAT3STAT1KDM4ERAB9APOLB
SCHEMBL2849607 0.83 STAT3 (0.58) STAT3STAT1KDM4ERAB9APOLB
SCHEMBL935287 0.82 TOP1 (0.55) KDM4ERAB9APOLBTOP1CYCS
SCHEMBL29660266 0.82 TOP1 (0.55) KDM4ERAB9APOLBTOP1CYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209789-A Preparation method and application of hydrogen bond self-assembled microporous organic framework 安徽工业大学 2023-12-12 — — CN claimed
CN-114949337-B Medical thermosensitive hydrogel dressing and preparation method thereof 上海交通大学 2023-11-21 — — CN claimed
CN-116902960-A N and S co-doped carbon material, preparation method and application thereof in zinc-air battery 大连民族大学 2023-10-20 — — CN claimed
CN-114497724-B Solid electrolyte and preparation method and application thereof 苏州大学张家港工业技术研究院 2023-05-23 — — CN claimed
CN-114497724-A Solid electrolyte and preparation method and application thereof 苏州大学张家港工业技术研究院 2022-05-13 — — CN claimed
CN-111261884-B Carbon material with yolk shell structure and preparation method and application thereof 中国科学院大连化学物理研究所 2021-02-12 — — CN claimed
CN-111261884-A Carbon material with yolk shell structure and preparation method and application thereof 中国科学院大连化学物理研究所 2020-06-09 — — CN claimed
US-9417241-B2 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine (TCPP) and kit for use with detecting cancer BIOAFFINITY TECHNOLOGIES, INC. (US) 2016-08-16 — — US claimed
EP-2372361-B1 Compositions and methods for detecting pre-cancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOMODA INC (US) 2014-08-06 — — EP claimed
US-8486656-B2 Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOMODA, INC. (US) 2013-07-16 — — US claimed
US-20120149057-A1 METHOD FOR PROGNOSING RESPONSE TO CANCER THERAPY WITH 5, 10, 15, 20-TETRAKIS (CARBOXYPHENYL) PORPHINE BIOMODA, INC. (US) 2012-06-14 — — US claimed
US-7960138-B2 Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOMODA, INC. (US) 2011-06-14 — — US claimed
US-20100216169-A1 Method for Detecting and Prognosing Pre-Cancerous Cells Using 5, 10, 15, 20-Tetrakis (Carboxyphenyl) Porphine BIOMODA, INC. (US) 2010-08-26 — — US claimed
US-7670799-B2 dissolving the TCPP in an aqueous alcoholic solution; efficient solubilizing, improved staining ; for detect dysplastic, pre-cancerous, and cancerous cells from various tissue samples both in vitro and in situ BIOMODA, INC. (US) 2010-03-02 — — US claimed
US-7384764-B2 Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOMODA, INC. (US) 2008-06-10 — — US claimed
US-20050079561-A1 Detecting cancerous and precancerous cells; obtain tissue sample, incubate with tetrakis dyes, rinse and remove unbound dye, detect fluorescence, fuorescence indicates cancerous or precancerous cells BIOMODA, INC. 2005-04-14 — — US claimed
US-6838248-B2 Detecting cancerous and precancerous cells; obtain tissue sample, incubate wih tetrakis dyes, rince and remove unbound dye, detect fluorescence, fuorescence indicates cancerous or precancerous cells BIOMODA, INC. (US) 2005-01-04 — — US claimed
JP-5115787-A — — None — — JP disclosed
EP-0057088-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-08-04 — — EP disclosed
US-4240920-A A SURFACTANT, A PEROXY BLEACH AND A PORPHINE BLEACH THE PROCTER & GAMBLE COMPANY (US) 1980-12-23 — — US disclosed
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