Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | SDHB | P21912 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271849 | 0.89 | STAT3 (0.51) | STAT3STAT1SLC6A3SLC6A4ABCG2 | |
| SCHEMBL1998702 | 0.86 | STAT3 (0.56) | STAT3STAT1KDM4E | |
| SCHEMBL29062206 | 0.85 | STAT3 (0.55) | STAT3STAT1KDM4E | |
| SCHEMBL30583773 | 0.85 | STAT3 (0.55) | STAT3STAT1KDM4E | |
| SCHEMBL1945082 | 0.83 | STAT3 (0.54) | STAT3STAT1SMN1; SMN2MEN1MAPT | |
| SCHEMBL30583769 | 0.82 | STAT3 (0.53) | STAT3STAT1KDM4E | |
| SCHEMBL30583768 | 0.81 | STAT3 (0.55) | STAT3STAT1KDM4E | |
| SCHEMBL2849607 | 0.79 | STAT3 (0.58) | STAT3STAT1SMN1; SMN2MEN1MAPT | |
| SCHEMBL6413587 | 0.79 | ABCG2 (0.43) | STAT3STAT1ABCG2SMN1; SMN2MAPT | |
| SCHEMBL27579991 | 0.79 | STAT3 (0.58) | STAT3STAT1SMN1; SMN2HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521551-B2 | Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-20080275232-A1 | CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. | 2008-11-06 | — | — | US | disclosed |
| US-20050020560-A1 | Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. | 2005-01-27 | — | — | US | disclosed |
| US-6794505-B1 | Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. | 2004-09-21 | — | — | US | disclosed |
| WO-2001074818-A1 | CHLORINS WITH FUSED RINGS FOR USE IN PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. (US) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275232-A1 | CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY | PPOX, HMBS, DDT | STAT3 3696/4885STAT1 3561/4885SLC6A3 1664/4885 |
| US-20050020560-A1 | Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy | PPOX, HMBS, DDT | STAT3 3916/4885STAT1 3672/4885SLC6A3 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.