SCHEMBL455572

SCHEMBL455572

O=C(O)c1ccccc1-c1cc2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ POLB P06746 1/20 0.45
▸ STAT3 P40763 1/20 0.39
▸ STAT1 P42224 1/20 0.39
▸ DHODH Q02127 10/20 0.37
▸ ADORA2B P29275 1/20 0.37
▸ FOLH1 Q04609 1/20 0.37
▸ CYP3A4 P08684 2/20 0.36
▸ CYP2C9 P11712 2/20 0.36
▸ ALOX12 P18054 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ USP2 O75604 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ EGFR P00533 1/20 0.35
▸ GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28919689 0.99 KDM4E (0.46) KDM4ERAB9APOLBSTAT3STAT1
SCHEMBL29253951 0.99 KDM4E (0.46) KDM4ERAB9APOLBSTAT3STAT1
Hydrochloric Acid SCHEMBL8765412 0.99 KDM4E (0.46) KDM4ERAB9APOLBSTAT3STAT1
SCHEMBL28827036 0.99 KDM4E (0.46) KDM4ERAB9APOLBSTAT3STAT1
Phthalic Acid SCHEMBL28444843 0.84 ALDH1A1 (0.48) KDM4ERAB9APOLBSTAT3STAT1
SCHEMBL27827077 0.84 STAT3 (0.37) KDM4EPOLBSTAT3STAT1MEN1
SCHEMBL1998702 0.83 STAT3 (0.56) KDM4ERAB9APOLBSTAT3STAT1
SCHEMBL1063740 0.82 STAT3 (0.33) KDM4ERAB9APOLBSTAT3STAT1
SCHEMBL30583773 0.82 STAT3 (0.55) KDM4ERAB9APOLBSTAT3STAT1
SCHEMBL29062206 0.82 STAT3 (0.55) KDM4ERAB9APOLBSTAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12461102-B2 Pristine graphene based biosensor for biomarker detection and related core particles, materials compositions methods and systems HAWKEYE BIO, LIMITED (IE) 2025-11-04 — — US claimed
WO-2024010609-A1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO, LIMITED (IE) 2024-01-11 — — WO claimed
CN-117209789-A Preparation method and application of hydrogen bond self-assembled microporous organic framework 安徽工业大学 2023-12-12 — — CN claimed
CN-117160248-A Nanofiltration membrane and preparation method and application thereof 南京大学 2023-12-05 — — CN claimed
CN-114949337-B Medical thermosensitive hydrogel dressing and preparation method thereof 上海交通大学 2023-11-21 — — CN claimed
EP-4271651-A1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO, LIMITED (IE) 2023-11-08 — — EP claimed
CN-113555564-B Preparation of supported non-noble metal electrocatalyst with MIL-88 as carrier and application of supported non-noble metal electrocatalyst in oxygen reduction reaction 大连民族大学 2023-06-20 — — CN claimed
CN-114497724-B Solid electrolyte and preparation method and application thereof 苏州大学张家港工业技术研究院 2023-05-23 — — CN claimed
WO-2022147171-A1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO, LIMITED (US) 2022-07-07 — — WO claimed
CN-114497724-A Solid electrolyte and preparation method and application thereof 苏州大学张家港工业技术研究院 2022-05-13 — — CN claimed
WO-2011028698-A2 MRI AND OPTICAL ASSAYS FOR PROTEASES KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-03-10 — — WO claimed
US-20110014125-A1 PROTEASE ASSAY KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-01-20 — — US claimed
EP-2260108-A2 PROTEASE ASSAY Kansas State University Research Foundation (US) 2010-12-15 — — EP claimed
US-20100216169-A1 Method for Detecting and Prognosing Pre-Cancerous Cells Using 5, 10, 15, 20-Tetrakis (Carboxyphenyl) Porphine BIOMODA, INC. (US) 2010-08-26 — — US claimed
US-7670799-B2 dissolving the TCPP in an aqueous alcoholic solution; efficient solubilizing, improved staining ; for detect dysplastic, pre-cancerous, and cancerous cells from various tissue samples both in vitro and in situ BIOMODA, INC. (US) 2010-03-02 — — US claimed
WO-2009111470-A2 PROTEASE ASSAY KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2009-09-11 — — WO claimed
US-7384764-B2 Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOMODA, INC. (US) 2008-06-10 — — US claimed
US-20050079561-A1 Detecting cancerous and precancerous cells; obtain tissue sample, incubate with tetrakis dyes, rinse and remove unbound dye, detect fluorescence, fuorescence indicates cancerous or precancerous cells BIOMODA, INC. 2005-04-14 — — US claimed
US-6838248-B2 Detecting cancerous and precancerous cells; obtain tissue sample, incubate wih tetrakis dyes, rince and remove unbound dye, detect fluorescence, fuorescence indicates cancerous or precancerous cells BIOMODA, INC. (US) 2005-01-04 — — US claimed
US-4541438-A Localization of cancerous tissue by monitoring infrared fluorescence emitted by intravenously injected porphyrin tumor-specific markers excited by long wavelength light THE JOHNS HOPKINS UNIVERSITY (US) 1985-09-17 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014125-A1 PROTEASE ASSAY PREP, TMPRSS15, PRSS3 KDM4E 3846/4885RAB9A 4308/4885POLB 908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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