Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 13/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102851 | 0.85 | PIM1 (1.00) | PIM1 | |
| SCHEMBL102616 | 0.81 | PIM1 (1.00) | PIM1DYRK1A | |
| SCHEMBL102542 | 0.79 | PIM1 (1.00) | PIM1 | |
| SCHEMBL15699138 | 0.76 | DYRK1A (0.76) | PIM1DYRK1AFYN | |
| SCHEMBL19987042 | 0.76 | PIM1 (0.76) | PIM1DYRK1AFYN | |
| SCHEMBL13867484 | 0.76 | PIM1 (0.87) | PIM1DYRK1A | |
| SCHEMBL2948807 | 0.76 | PIM1 (1.00) | PIM1FYN | |
| SCHEMBL102421 | 0.75 | DYRK1A (0.91) | PIM1DYRK1AFYN | |
| SCHEMBL23299250 | 0.75 | PIM1 (0.81) | PIM1 | |
| SCHEMBL29436156 | 0.74 | DYRK1A (0.73) | PIM1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734205-B1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | TOLERO PHARMACEUTICALS INC (US) | 2018-03-21 | — | — | EP | disclosed |