Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16845906 | 1.00 | LMNA (0.33) | LMNAHPGDSDAOCES2 | |
| SCHEMBL456619 | 0.81 | — | — | |
| SCHEMBL7526154 | 0.81 | LMNA (0.42) | LMNAHPGDSCES2 | |
| SCHEMBL2720308 | 0.79 | MAPT (0.38) | LMNA | |
| SCHEMBL19272362 | 0.79 | MAPT (0.38) | LMNA | |
| SCHEMBL12930768 | 0.79 | DAO (0.33) | DAO | |
| SCHEMBL12384730 | 0.79 | MAPT (0.38) | LMNA | |
| SCHEMBL19791203 | 0.78 | LMNA (0.32) | LMNA | |
| SCHEMBL22025307 | 0.78 | LMNA (0.32) | LMNA | |
| SCHEMBL18032443 | 0.78 | LMNA (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734205-B1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | TOLERO PHARMACEUTICALS INC (US) | 2018-03-21 | — | — | EP | disclosed |