Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456619 | 0.79 | — | — | |
| SCHEMBL7526154 | 0.79 | LMNA (0.42) | LMNA | |
| SCHEMBL16845906 | 0.78 | LMNA (0.33) | LMNA | |
| SCHEMBL19987184 | 0.78 | LMNA (0.33) | LMNA | |
| SCHEMBL19791203 | 0.76 | LMNA (0.32) | LMNA | |
| SCHEMBL18032443 | 0.76 | LMNA (0.32) | LMNA | |
| SCHEMBL16855784 | 0.74 | HTT (0.37) | LMNA | |
| SCHEMBL17739256 | 0.73 | EPHX1 (0.32) | LMNA | |
| SCHEMBL18959370 | 0.73 | MEN1 (0.33) | LMNA | |
| SCHEMBL7513835 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3059238-B1 | FUSED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF | SHANGHAI YINGLI PHARM CO LTD (CN) | 2020-05-27 | — | — | EP | disclosed |