SCHEMBL19987276

SCHEMBL19987276

CCCCCCc1ccc(Nc2ccc(C)cc2)cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
MAPT P10636 3/20 0.58
CYP3A4 P08684 2/20 0.58
HTT P42858 2/20 0.58
TP53 P04637 1/20 0.58
ALOX5 P09917 1/20 0.58
ALOX15 P16050 1/20 0.58
TSHR P16473 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
GAA P10253 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
G6PD P11413 1/20 0.42
CNR2 P34972 8/20 0.42
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
USP2 O75604 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986528 0.88 TYR (0.58) TYRMEN1KMT2AMAPTCYP3A4
SCHEMBL19985673 0.87 TYR (0.56) TYRMEN1KMT2AMAPTCYP3A4
SCHEMBL25572272 0.85 MEN1 (0.45) TYRMEN1KMT2AMAPTCYP3A4
SCHEMBL19985677 0.85 TYR (0.57) TYRMEN1KMT2AMAPTCYP3A4
SCHEMBL9504248 0.82 TYR (0.71) TYRMEN1KMT2AMAPTCYP3A4
SCHEMBL8402868 0.82 TYR (0.71) TYRMEN1KMT2AMAPTCYP3A4
SCHEMBL3358965 0.82 TYR (0.71) TYRMEN1KMT2AMAPTCYP3A4
SCHEMBL8590686 0.82 TYR (0.71) TYRMEN1KMT2AMAPTCYP3A4
Amylmetacresol SCHEMBL29897625 0.81 TYR (0.68) TYRMEN1KMT2AMAPTCYP3A4
Amylmetacresol SCHEMBL302197 0.81 TYR (0.68) TYRMEN1KMT2AMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3516019-B1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS CORP (US) 2023-06-14 EP disclosed
EP-3516020-B1 ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS LANXESS CORP (US) 2022-05-25 EP disclosed
US-10723969-B2 Lubricant compositions stabilized by mixtures of diarylamine and hydroxydiarylamine antioxidants LANXESS SOLUTIONS US INC. (US) 2020-07-28 US disclosed
US-10563145-B2 Alkylated 3-hydroxydiphenylamine antioxidants LANXESS SOLUTIONS US INC. (US) 2020-02-18 US disclosed
WO-2018057366-A1 ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. (US) 2018-03-29 WO disclosed
WO-2018057364-A1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. (US) 2018-03-29 WO disclosed
US-20180079987-A1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. 2018-03-22 US disclosed
US-20180079985-A1 ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180079985-A1 ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS GPX4, GSTO1, LPO TYR 11/4885MEN1 4320/4885KMT2A 1708/4885
US-10563145-B2 Alkylated 3-hydroxydiphenylamine antioxidants GPX4, GSTO1, LPO TYR 11/4885MEN1 4320/4885KMT2A 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.