SCHEMBL19987340

SCHEMBL19987340

Cc1ccc(Nc2ccc(C(C)(C)C)cc2O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HSD17B2 P37059 2/20 0.48
TSHR P16473 1/20 0.45
AKR1C3 P42330 3/20 0.43
AKR1C2 P52895 3/20 0.43
MAPK1 P28482 1/20 0.43
GAA P10253 5/20 0.43
MAPT P10636 5/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
KDM4E B2RXH2 2/20 0.43
RECQL P46063 2/20 0.43
G6PD P11413 1/20 0.43
POLB P06746 1/20 0.43
CASP6 P55212 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985670 0.87 ALDH1A1 (0.48) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL19985672 0.78 HPGD (0.44) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL18365185 0.78 AKR1C3 (0.44) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL23432311 0.78 TSHR (0.47) ALDH1A1TDP1HSD17B2TSHRAKR1C3
SCHEMBL28194326 0.77 AKR1C3 (0.49) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL17858235 0.76 RAPGEF4 (0.52) ALDH1A1HSD17B2TSHRAKR1C3AKR1C2
SCHEMBL12278117 0.76 TSHR (0.71) TDP1HPGDTSHRMAPK1GAA
SCHEMBL25458273 0.75 HPGD (0.44) ALDH1A1TDP1HPGDTSHRAKR1C3
SCHEMBL15457920 0.74 ALDH1A1 (0.59) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL21392342 0.74 HSD17B2 (0.55) ALDH1A1TDP1HSD17B2TSHRAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10723969-B2 Lubricant compositions stabilized by mixtures of diarylamine and hydroxydiarylamine antioxidants LANXESS SOLUTIONS US INC. (US) 2020-07-28 US disclosed
US-20180079987-A1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. 2018-03-22 US disclosed