SCHEMBL16273679

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16273618	0.93	PDE4A (0.38)	HPGDPSEN1PSEN2APH1BNCSTN
	SCHEMBL16273684	0.91	MRGPRX4 (0.38)	HPGDMRGPRX4P2RX3PSDCD274
	SCHEMBL16910707	0.91	MRGPRX4 (0.34)	HPGDPSEN1PSEN2APH1BNCSTN
	SCHEMBL16273667	0.90	MRGPRX4 (0.35)	HPGDMRGPRX4CD274
	SCHEMBL16273688	0.90	MRGPRX4 (0.35)	HPGDMRGPRX4MAPTKDM4EP2RX3
	SCHEMBL16627196	0.89	MRGPRX4 (0.35)	HPGDMRGPRX4MAPTMAPK1ALDH1A1
	SCHEMBL16910786	0.87	NR1H4 (0.37)	MRGPRX4ALDH1A1PDE4APDE4BPDE4C
	SCHEMBL16273737	0.87	HPGD (0.36)	HPGDMRGPRX4MAPTALDH1A1KDM4E
	SCHEMBL17600083	0.87	MRGPRX4 (0.36)	HPGDMRGPRX4MAPTKDM4EPOLB
	SCHEMBL19987549	0.86	HPGD (0.35)	HPGDMRGPRX4MAPTKDM4EP2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.