Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GLB1 | P16278 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18121287 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GLB1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL20033544 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GLB1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL7987844 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GLB1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL7150901 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GLB1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL31571169 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GLB1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL7991319 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GLB1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL7150801 | 0.88 | ALDH1A1 (0.43) | ALDH1A1GLB1HPGDMEN1POLB | |
| SCHEMBL11301737 | 0.85 | ALDH1A1 (0.48) | ALDH1A1GLB1HPGDMEN1POLB | |
| SCHEMBL18121282 | 0.85 | ALDH1A1 (0.47) | ALDH1A1GLB1HPGDMEN1POLB | |
| SCHEMBL7154831 | 0.83 | POLB (0.48) | ALDH1A1TXNRD1TXNRD3TXNRD2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10668169-B2 | Micelle composition for nucleic acid delivery using temperature-sensitive polymer and method for producing same | THE UNIVERSITY OF TOKYO (JP) | 2020-06-02 | — | — | US | disclosed |
| US-20180289835-A1 | MICELLE COMPOSITION FOR NUCLEIC ACID DELIVERY USING TEMPERATURE-SENSITIVE POLYMER AND METHOD FOR PRODUCING SAME | THE UNIVERSITY OF TOKYO (JP) | 2018-10-11 | — | — | US | disclosed |
| EP-3299020-A1 | MICELLE COMPOSITION FOR NUCLEIC ACID DELIVERY USING TEMPERATURE-SENSITIVE POLYMER AND METHOD FOR PRODUCING SAME | THE UNIVERSITY OF TOKYO (JP) | 2018-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10668169-B2 | Micelle composition for nucleic acid delivery using temperature-sensitive polymer and method for producing same | POLRMT, LEO1, DLST | ALDH1A1 4853/4885GLB1 2225/4885TXNRD1 4420/4885 |
| US-20180289835-A1 | MICELLE COMPOSITION FOR NUCLEIC ACID DELIVERY USING TEMPERATURE-SENSITIVE POLYMER AND METHOD FOR PRODUCING SAME | POLRMT, LEO1, DLST | ALDH1A1 4853/4885GLB1 2225/4885TXNRD1 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.