Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154024 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 | |
| SCHEMBL29603877 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 | |
| SCHEMBL29466520 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 | |
| SCHEMBL29604345 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 | |
| SCHEMBL5154287 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 | |
| SCHEMBL28557394 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 | |
| SCHEMBL7768868 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 | |
| SCHEMBL5150298 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 | |
| SCHEMBL240845 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 | |
| SCHEMBL3757758 | 1.00 | LMNA (0.40) | LMNAHIF1AEPAS1TRPV1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180147138-A1 | TRANSDERMAL LIQUID PREPARATION | MEDRX CO., LTD (JP) | 2018-05-31 | — | — | US | disclosed |
| EP-3299012-A1 | TRANSDERMAL LIQUID PREPARATION | MEDRx Co., Ltd. (JP) | 2018-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147138-A1 | TRANSDERMAL LIQUID PREPARATION | PHOSPHO1, PCTP, NAPEPLD | LMNA 2258/4885HIF1A 4610/4885EPAS1 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.