SCHEMBL19988074

SCHEMBL19988074

Cc1nc(CI)nc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.53
ALDH1A1 P00352 4/20 0.53
CYP1A2 P05177 3/20 0.53
HPGD P15428 2/20 0.53
NUDT1 P36639 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MPO P05164 1/20 0.45
RAD52 P43351 1/20 0.45
KDM4E B2RXH2 3/20 0.41
POLB P06746 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GAA P10253 1/20 0.40
NPC1 O15118 2/20 0.40
MAPK1 P28482 2/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14985883 0.82 GPR3 (0.55) GPR3ALDH1A1CYP1A2HPGDNUDT1
SCHEMBL15083814 0.81 ALDH1A1 (0.58) GPR3ALDH1A1CYP1A2HPGDNUDT1
SCHEMBL16432784 0.81 GPR3 (0.53) GPR3ALDH1A1CYP1A2HPGDNUDT1
SCHEMBL637147 0.81 GPR3 (0.53) GPR3ALDH1A1CYP1A2HPGDNUDT1
SCHEMBL17194216 0.81 GPR3 (0.53) GPR3ALDH1A1CYP1A2HPGDNUDT1
SCHEMBL29693664 0.81 GPR3 (0.53) GPR3ALDH1A1CYP1A2HPGDNUDT1
SCHEMBL17904025 0.79 ALDH1A1 (0.56) GPR3ALDH1A1CYP1A2HPGDNUDT1
SCHEMBL28005447 0.78 ALDH1A1 (0.50) GPR3ALDH1A1CYP1A2HPGDNUDT1
SCHEMBL19267960 0.78 ALDH1A1 (0.50) GPR3ALDH1A1CYP1A2HPGDNUDT1
SCHEMBL8277836 0.77 ALDH1A1 (0.53) GPR3ALDH1A1CYP1A2HPGDNUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3296288-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2018-03-21 EP disclosed
CN-103254192-B Xanthine derivative, its salt, intermediate, preparation method and application SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) 2015-12-02 CN disclosed
CN-103254193-B Xanthine compound intermediate and preparation method thereof SHANGHAI INST PHARM INDUSTRY 2015-04-22 CN disclosed
CN-103254193-A Xanthine compound intermediate and preparation method thereof SHANGHAI INST PHARM INDUSTRY 2013-08-21 CN disclosed
CN-103254192-A Xanthine compound, its salt, intermediates, preparation method and application SHANGHAI INST PHARM INDUSTRY 2013-08-21 CN disclosed