SCHEMBL19990752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4117648	0.84	ALDH1A1 (0.44)	ERN1ALDH1A1POLBRAB9ACA12
	SCHEMBL31306269	0.84	ERN1 (0.48)	ERN1ALDH1A1POLBRAB9ACA12
	SCHEMBL19998358	0.84	ALDH1A1 (0.44)	ERN1ALDH1A1POLBRAB9ACA12
	SCHEMBL852311	0.82	GAA (0.47)	ERN1ALDH1A1POLBRAB9ACA12
	SCHEMBL23364530	0.82	KDM4E (0.58)	ERN1ALDH1A1POLBKDM4ETSHR
	SCHEMBL829753	0.82	CA12 (0.54)	ALDH1A1POLBCA12CA1CA2
	SCHEMBL13473596	0.80	ALDH1A1 (0.50)	ERN1ALDH1A1POLBRAB9AHCRTR1
	SCHEMBL21574949	0.79	ALDH1A1 (0.40)	ERN1ALDH1A1POLBRAB9ACA12
	SCHEMBL31336100	0.79	ERN1 (0.51)	ERN1ALDH1A1POLBRAB9ACA12
	SCHEMBL1161943	0.79	ERN1 (0.51)	ERN1ALDH1A1POLBRAB9ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.