Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009187 | 0.89 | PLA2G10 (0.36) | — | |
| SCHEMBL22368509 | 0.88 | KCNA5 (0.35) | KCNA5DHFR | |
| SCHEMBL19990609 | 0.88 | KCNA5 (0.35) | KCNA5DHFR | |
| SCHEMBL20009186 | 0.85 | FKBP1A (0.38) | KCNA5DHFR | |
| SCHEMBL19990723 | 0.82 | KCNA5 (0.32) | KCNA5 | |
| SCHEMBL20009179 | 0.80 | KCNA5 (0.37) | KCNA5DHFR | |
| SCHEMBL22368502 | 0.80 | KCNA5 (0.37) | KCNA5DHFR | |
| SCHEMBL22368497 | 0.80 | ALOX15 (0.35) | KCNA5DHFR | |
| SCHEMBL19990666 | 0.80 | ALOX15 (0.35) | KCNA5DHFR | |
| SCHEMBL22368496 | 0.78 | KCNA5 (0.37) | KCNA5DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698796-B1 | PHARMACEUTICAL COMBINATION OF A TRICYCLIC BETA-LACTAMASE INHIBITOR WITH SPECIFIC BETA-LACTAM ANTIBIOTICS | NOVARTIS AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| EP-3698796-A1 | PHARMACEUTICAL COMBINATION OF A TRICYCLIC BETA-LACTAMASE INHIBITOR WITH SPECIFIC BETA-LACTAM ANTIBIOTICS | Novartis AG (CH) | 2020-08-26 | — | — | EP | disclosed |
| EP-3519419-B1 | BETA-LACTAMASE INHIBITORS | NOVARTIS AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| US-10597396-B2 | Beta-lactamase inhibitors | NOVARTIS AG (CH) | 2020-03-24 | — | — | US | disclosed |
| US-20190177324-A1 | BETA-LACTAMASE INHIBITORS | NOVARTIS AG (CH) | 2019-06-13 | — | — | US | disclosed |
| US-10065957-B2 | Beta-lactamase inhibitors | NOVARTIS AG (CH) | 2018-09-04 | — | — | US | disclosed |
| US-20180086762-A1 | BETA-LACTAMASE INHIBITORS | NOVARTIS AG (CH) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177324-A1 | BETA-LACTAMASE INHIBITORS | MGAM, LCT, GAA | KCNA5 2796/4885DHFR 516/4885 |
| US-10597396-B2 | Beta-lactamase inhibitors | MGAM, LCT, GAA | KCNA5 2796/4885DHFR 516/4885 |
| US-20180086762-A1 | BETA-LACTAMASE INHIBITORS | MGAM, LCT, GAA | KCNA5 2796/4885DHFR 516/4885 |
| US-10065957-B2 | Beta-lactamase inhibitors | MGAM, LCT, GAA | KCNA5 2796/4885DHFR 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.