Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | QDPR | P09417 | 2/20 | 0.50 |
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81500 | 0.92 | QDPR (0.56) | SLC18A3QDPRLSSRAB9AHTT | |
| SCHEMBL23469162 | 0.85 | SLC6A2 (0.55) | LSSRAB9AHTTALDH1A1PROKR1 | |
| SCHEMBL12950820 | 0.85 | SLC6A2 (0.55) | LSSRAB9AHTTALDH1A1PROKR1 | |
| SCHEMBL23442954 | 0.84 | LSS (0.65) | SLC18A3QDPRLSSPROKR1 | |
| SCHEMBL13015008 | 0.84 | QDPR (0.49) | QDPRLSSAPOBEC3AAPOBEC3GATM | |
| SCHEMBL9910976 | 0.83 | DRD2 (0.56) | SLC18A3SMN1; SMN2TSHR | |
| SCHEMBL610439 | 0.82 | QDPR (0.47) | SLC18A3QDPRLSSAPOBEC3AAPOBEC3G | |
| SCHEMBL14544198 | 0.81 | RAB9A (0.50) | SLC18A3QDPRLSSRAB9AHTT | |
| SCHEMBL23443509 | 0.81 | DRD2 (0.60) | QDPRLSSALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL610312 | 0.80 | QDPR (0.45) | QDPRLSSAPOBEC3AAPOBEC3GALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036386-A1 | ISOINDOLIN-1-ON DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT FOR PREVENTING OR TREATING CANCER | 한국화학연구원 | 2020-02-20 | — | — | WO | disclosed |
| WO-2018053373-A1 | USES OF SATL-INDUCIBLE KINASE (SIK) INHIBITORS FOR TREATING OSTEOPOROSIS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-03-22 | — | — | WO | disclosed |