Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 2/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24765276 | 0.82 | CHEK1 (0.59) | AKT2CHEK1XDHDYRK1AIKBKE | |
| SCHEMBL20213984 | 0.75 | AKT2 (0.62) | AKT2CHEK1IKBKBIKBKEPIM1 | |
| SCHEMBL30829475 | 0.75 | AKT2 (0.62) | AKT2CHEK1IKBKBIKBKEPIM1 | |
| SCHEMBL13035810 | 0.75 | AKT2 (0.67) | AKT2CHEK1IKBKBIKBKE | |
| SCHEMBL25836130 | 0.73 | DHODH (0.49) | KCNH2SCN10AXDHNPY5RDYRK1A | |
| SCHEMBL16115987 | 0.72 | IKBKB (0.71) | AKT2CHEK1IKBKBIKBKEMAPK1 | |
| SCHEMBL26832622 | 0.72 | AKT2 (0.62) | AKT2CHEK1IKBKBIKBKEROCK1 | |
| SCHEMBL5542229 | 0.72 | PTGES2 (0.50) | KCNH2SCN10AXDHDYRK1APIM1 | |
| SCHEMBL31687949 | 0.71 | XDH (0.41) | KCNH2SCN10AUSP7XDHNPY5R | |
| SCHEMBL873114 | 0.70 | AKT2 (1.00) | AKT2CHEK1IKBKBDYRK1AIKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051252-A2 | NOVEL AMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, AND MITICIDE | INSECTICIDES (INDIA) LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |