SCHEMBL1999286

SCHEMBL1999286

CC(C)c1cnc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.49
ADORA2A P29274 1/20 0.49
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
MAPK14 Q16539 14/20 0.40
MAPK10 P53779 3/20 0.40
KDM5B Q9UGL1 1/20 0.40
MAPK13 O15264 2/20 0.38
MAPK12 P53778 2/20 0.38
MAPK11 Q15759 2/20 0.38
MAPK9 P45984 1/20 0.38
CSNK1D P48730 1/20 0.38
GCGR P47871 1/20 0.38
CNR1 P21554 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15679983 0.94 CNR1 (0.46) ADORA1ADORA2APTGS1PTGS2HTR2A
SCHEMBL4788899 0.86 ADORA1 (0.41) ADORA1ADORA2APTGS1PTGS2HTR2A
SCHEMBL24046599 0.81 CKS1B (0.53) ADORA1ADORA2AKDM5BCNR1
SCHEMBL10511267 0.79 ALDH1A1 (0.47) ADORA1KDM5BCNR1
SCHEMBL15679991 0.76 ADORA2A (0.42) ADORA1ADORA2APTGS1PTGS2HTR2A
SCHEMBL12077150 0.76 ADORA2A (0.64) ADORA1ADORA2AMAPK14MAPK10MAPK13
SCHEMBL1999851 0.76 ADORA1 (0.46) ADORA1ADORA2AHTR2AHTR2CHTR2B
SCHEMBL27903531 0.73 MAPK1 (0.42) PTGS1PTGS2MAPK14
SCHEMBL22184930 0.72 GPR55 (0.40) PTGS1PTGS2
SCHEMBL5211789 0.72 ADORA1 (0.42) ADORA1ADORA2AMAPK14MAPK10MAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9653692-B2 Light-emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-16 US disclosed
US-9653692-B2 Light-emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-16 US disclosed
US-9653692-B2 Light-emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-16 US disclosed
US-20160155960-A1 Light-Emitting Device and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-06-02 US disclosed
US-20160155960-A1 Light-Emitting Device and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-06-02 US disclosed
US-20160155960-A1 Light-Emitting Device and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-06-02 US disclosed
US-9257657-B2 Light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-02-09 US disclosed
US-9257657-B2 Light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-02-09 US disclosed
US-8889266-B2 Organometallic complex, and light-emitting element, light-emitting device and electronic-device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-11-18 US disclosed
US-8889266-B2 Organometallic complex, and light-emitting element, light-emitting device and electronic-device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-11-18 US disclosed
EP-1869059-B1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE USING THE ORGANOMETALLIC COMPLEX SEMICONDUCTOR ENERGY LAB (JP) 2014-04-23 EP disclosed
US-7960038-B2 Light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-06-14 US disclosed
US-7960038-B2 Light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-06-14 US disclosed
US-7960038-B2 Light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-06-14 US disclosed
US-20090015143-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic- Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-15 US disclosed
US-20090015143-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic- Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-15 US disclosed
US-20090015143-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic- Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-15 US disclosed
EP-1869059-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE USING THE ORGANOMETALLIC COMPLEX SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-12-26 EP disclosed
US-20060263636-A1 Light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2006-11-23 US disclosed
WO-2006098460-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE USING THE ORGANOMETALLIC COMPLEX SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090015143-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic- Device Using the Organometallic Complex LIG3, CRY1, MCM3 ADORA1 4038/4885ADORA2A 4618/4885PTGS1 3414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.