Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19992867 | 0.77 | TDP1 (0.54) | TDP1ATMMEN1KMT2ATSHR | |
| SCHEMBL18416407 | 0.77 | TDP1 (0.54) | TDP1ATMMEN1KMT2ATSHR | |
| SCHEMBL646260 | 0.74 | TDP1 (0.44) | TDP1ATMTSHRHSD17B10ALDH1A1 | |
| SCHEMBL21891545 | 0.74 | CA12 (0.47) | TDP1ATMTSHRHSD17B10ALDH1A1 | |
| SCHEMBL21870773 | 0.72 | TDP1 (0.43) | TDP1ATMMEN1KMT2ATSHR | |
| SCHEMBL20213681 | 0.71 | ALDH1A1 (0.60) | TDP1ATMMEN1KMT2ATSHR | |
| SCHEMBL20213682 | 0.71 | ALDH1A1 (0.60) | TDP1ATMMEN1KMT2ATSHR | |
| SCHEMBL42138 | 0.70 | TDP1 (0.64) | TDP1ATMMEN1KMT2ATSHR | |
| SCHEMBL5993024 | 0.69 | CA12 (0.42) | TDP1ATMTSHRHSD17B10ALDH1A1 | |
| SCHEMBL21162820 | 0.69 | TDP1 (0.55) | TDP1ATMMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109794292-A | Z- selectivity ruthenium Cabbeen olefin metathesis catalyst and the preparation method and application thereof | 天津大学 | 2019-05-24 | — | — | CN | disclosed |