Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230273 | 0.79 | ALDH1A1 (0.49) | GAAALDH1A1SMN1; SMN2TP53PKM | |
| SCHEMBL2502593 | 0.77 | ALDH1A1 (0.47) | GAAALDH1A1SMN1; SMN2TP53PKM | |
| SCHEMBL11408510 | 0.77 | ALDH1A1 (0.51) | GAAALDH1A1SMN1; SMN2TP53PKM | |
| SCHEMBL21279548 | 0.76 | CES2 (0.38) | SMN1; SMN2TP53KDM4EMAPTRAB9A | |
| SCHEMBL9229810 | 0.76 | KEAP1 (0.52) | GAAALDH1A1TP53HTTLMNA | |
| Hydrochloric Acid SCHEMBL840283 | 0.76 | ALDH1A1 (0.46) | GAAALDH1A1SMN1; SMN2TP53PKM | |
| SCHEMBL17073475 | 0.75 | — | — | |
| SCHEMBL254224 | 0.74 | — | — | |
| SCHEMBL10983413 | 0.74 | ALDH1A1 (0.57) | GAAALDH1A1SMN1; SMN2TP53PKM | |
| SCHEMBL20620433 | 0.74 | GAA (0.45) | GAAALDH1A1SMN1; SMN2TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927214-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |