Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 8/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19993456 | 0.86 | POLB (0.43) | POLBKDM4EALDH1A1MAPTGRIN1 | |
| SCHEMBL22775915 | 0.85 | POLB (0.41) | POLBKCNQ3KCNQ2PTGS2PDE10A | |
| SCHEMBL24868773 | 0.83 | POLB (0.41) | POLBKDM4EALDH1A1GRIN1GRIN2B | |
| SCHEMBL21265226 | 0.82 | POLB (0.41) | POLBKDM4EALDH1A1GRIN1GRIN2B | |
| SCHEMBL19993247 | 0.82 | HTR6 (0.35) | HTR6PTGS2RAB9A | |
| SCHEMBL24868761 | 0.81 | POLB (0.41) | POLBPDE10AKDM4EALDH1A1RAB9A | |
| SCHEMBL24868760 | 0.81 | POLB (0.40) | POLBALDH1A1MAPTRAB9APKM | |
| SCHEMBL24868767 | 0.81 | POLB (0.40) | POLBALDH1A1RAB9APKM | |
| SCHEMBL23956606 | 0.80 | POLB (0.39) | POLBKCNQ3KCNQ2PDE10AALDH1A1 | |
| SCHEMBL19993254 | 0.80 | POLB (0.42) | POLBHTR6PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515921-B1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-10611779-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-04-07 | — | — | US | disclosed |
| US-20190248811-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-15 | — | — | US | disclosed |
| WO-2018050825-A1 | PYRAZOLO [1,5-A]PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10611779-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, BCHE, ACHE | POLB 3706/4885HTR6 4745/4885KCNQ3 730/4885 |
| US-20190248811-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, BCHE, ACHE | POLB 3706/4885HTR6 4745/4885KCNQ3 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.