SCHEMBL24868773

SCHEMBL24868773

CCS(=O)(=O)c1c(-c2nc3cc(C(F)(F)F)cnc3n2C)nn2ccc(C(F)(F)F)cc12

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.41
▸ S1PR1 P21453 7/20 0.35
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ GRIN1 Q05586 6/20 0.32
▸ GRIN2B Q13224 6/20 0.32
▸ PKM P14618 1/20 0.31
▸ MAOB P27338 1/20 0.31
▸ DDR1 Q08345 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21265226 0.94 POLB (0.41) POLBS1PR1KDM4EALDH1A1GRIN1
SCHEMBL24868767 0.92 POLB (0.40) POLBS1PR1ALDH1A1PKMMAOB
SCHEMBL24868760 0.92 POLB (0.40) POLBS1PR1ALDH1A1PKMDDR1
SCHEMBL19993456 0.90 POLB (0.43) POLBS1PR1KDM4EALDH1A1GRIN1
SCHEMBL24868761 0.87 POLB (0.41) POLBS1PR1KDM4EALDH1A1PKM
SCHEMBL20636704 0.84 POLB (0.40) POLBS1PR1ALDH1A1
SCHEMBL24868774 0.84 POLB (0.40) POLBS1PR1ALDH1A1MAOBDDR1
SCHEMBL19993455 0.84 POLB (0.40) POLBS1PR1ALDH1A1PKMDDR1
SCHEMBL19993256 0.83 POLB (0.41) POLBKDM4EALDH1A1GRIN1GRIN2B
SCHEMBL20636713 0.81 POLB (0.36) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2025-05-08 — — US claimed
EP-4475680-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL Syngenta Crop Protection AG (CH) 2024-12-18 — — EP claimed
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-11-28 — — US claimed
CN-118922081-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-11-08 — — CN claimed
US-20240268386-A1 SEED TREATMENT COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-08-15 — — US claimed
US-20240260577-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-08-08 — — US claimed
CN-117998986-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-05-07 — — CN claimed
CN-117320552-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2023-12-29 — — CN claimed
CN-117320551-A Seed treatment composition 先正达农作物保护股份公司 2023-12-29 — — CN claimed
WO-2023152340-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-08-17 — — WO claimed
WO-2023105065-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-06-15 — — WO claimed
WO-2023105064-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-06-15 — — WO claimed
WO-2022268815-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2022-12-29 — — WO claimed
WO-2022200364-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2022-09-29 — — WO claimed
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2025-05-08 — — US disclosed
WO-2025090578-A1 HETEROCYCLIC HYDRAZONES AS NEMATICIDES FMC CORPORATION (US) 2025-05-01 — — WO disclosed
EP-4475680-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL Syngenta Crop Protection AG (CH) 2024-12-18 — — EP disclosed
WO-2022268815-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2022-12-29 — — WO disclosed
WO-2022238576-A1 SEED TREATMENT COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-11-17 — — WO disclosed
WO-2022200364-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2022-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240260577-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL H1-2, H1-0, H1-3 POLB 4393/4885S1PR1 449/4885KDM4E 2843/4885
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAT1 POLB 4410/4885S1PR1 2226/4885KDM4E 2817/4885
US-20240268386-A1 SEED TREATMENT COMPOSITIONS FAU, ARF5, BROX POLB 846/4885S1PR1 2416/4885KDM4E 4283/4885
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAA2 POLB 4472/4885S1PR1 1668/4885KDM4E 3450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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