SCHEMBL19993501

SCHEMBL19993501

C=C/C=C\c1c(C)n(-c2ccccc2)c2c1ccc1c3ccccc3n(-c3ccc(-c4ccc(-n5c6ccccc6c6ccc7c8ccccc8n(-c8ccccc8)c7c65)cc4)cc3)c12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
AVPR1A P37288 1/20 0.33
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
HDAC4 P56524 1/20 0.32
KMT2A Q03164 1/20 0.32
PLA2G2A P14555 1/20 0.31
MAPT P10636 1/20 0.31
HTR7 P34969 1/20 0.30
RECQL P46063 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
GLA P06280 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25132238 0.95 KDM4E (0.42) KDM4EATML3MBTL1KMT2APLA2G2A
SCHEMBL24684886 0.91 KDM4E (0.35) KDM4EATML3MBTL1AVPR1AAKR1C4
SCHEMBL22460115 0.90 KDM4E (0.33) KDM4EATML3MBTL1KMT2A
SCHEMBL19646318 0.88 AVPR1A (0.33) KDM4EATML3MBTL1AVPR1AAKR1C4
SCHEMBL20989408 0.88 AVPR1A (0.35) KDM4EATML3MBTL1AVPR1AKMT2A
SCHEMBL25488021 0.85 KDM4E (0.33) KDM4EATML3MBTL1AVPR1AAKR1C4
SCHEMBL24923159 0.85 KDM4E (0.31) KDM4EALDH1A1
SCHEMBL19649494 0.85 KDM4E (0.38) KDM4EATML3MBTL1AVPR1AAKR1C4
SCHEMBL18639104 0.85 L3MBTL1 (0.34) KDM4EATML3MBTL1AVPR1AKMT2A
SCHEMBL18544755 0.85 KDM4E (0.34) KDM4EATML3MBTL1AKR1C4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2021-07-20 US disclosed
US-20180083205-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same EPCAM, ILK, PPOX KDM4E 2903/4885ATM 2002/4885L3MBTL1 629/4885
US-20180083205-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EPCAM, ILK, PPOX KDM4E 2892/4885ATM 1912/4885L3MBTL1 604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.