Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.57 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.57 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.57 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.56 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.53 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.51 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16374042 | 0.91 | P2RX1 (0.58) | P2RX3P2RX4P2RX1P2RX2P2RY1 | |
| SCHEMBL16490112 | 0.91 | P2RX1 (0.58) | P2RX3P2RX4P2RX1P2RX2P2RY1 | |
| SCHEMBL15070749 | 0.91 | P2RX1 (0.58) | P2RX3P2RX4P2RX1P2RX2P2RY1 | |
| SCHEMBL16490101 | 0.85 | P2RX1 (0.57) | P2RX3P2RX4P2RX1P2RX2P2RY1 | |
| SCHEMBL15070750 | 0.85 | P2RX1 (0.57) | P2RX3P2RX4P2RX1P2RX2P2RY1 | |
| SCHEMBL16368340 | 0.84 | P2RY1 (0.55) | P2RX3P2RX4P2RX1P2RX2P2RY1 | |
| SCHEMBL16368319 | 0.84 | P2RX3 (0.60) | P2RX3P2RX4P2RX1P2RX2P2RY1 | |
| SCHEMBL16374216 | 0.84 | P2RX3 (0.60) | P2RX3P2RX4P2RX1P2RX2P2RY1 | |
| SCHEMBL16374061 | 0.83 | P2RY1 (0.58) | P2RX3P2RX4P2RX1P2RX2P2RY1 | |
| SCHEMBL15070748 | 0.83 | P2RX1 (0.57) | P2RX3P2RX4P2RX1P2RX2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079774-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079774-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C3B | P2RX3 90/4885P2RX4 75/4885P2RX1 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.