Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 2/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31751098 | 0.79 | GRIK1 (0.38) | ERCC1ERCC5FEN1ERCC4PARP1 | |
| SCHEMBL6670689 | 0.76 | ALDH1A1 (0.40) | ERCC1ERCC5FEN1ERCC4PARP15 | |
| SCHEMBL2980047 | 0.71 | ALDH1A1 (0.54) | ERCC1ERCC5FEN1ERCC4PARP1 | |
| SCHEMBL2987031 | 0.70 | PARP15 (0.41) | ERCC1ERCC5FEN1ERCC4PARP1 | |
| SCHEMBL7507593 | 0.70 | DAO (0.53) | ERCC1ERCC5FEN1ERCC4PARP1 | |
| SCHEMBL31257840 | 0.66 | TNKS2 (0.45) | ERCC1ERCC5FEN1ERCC4PARP1 | |
| SCHEMBL8141804 | 0.66 | PARP1 (0.40) | ERCC1ERCC5FEN1ERCC4PARP1 | |
| SCHEMBL116024 | 0.64 | METAP2 (0.39) | ERCC1ERCC5FEN1ERCC4ALDH1A1 | |
| SCHEMBL6242682 | 0.62 | CYP1A2 (0.64) | ERCC1ERCC5FEN1ERCC4KMT2A | |
| SCHEMBL4175626 | 0.61 | MEN1 (0.62) | KMT2AALDH1A1MEN1MAPK1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515919-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018054846-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |