Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6297011 | 1.00 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL16293715 | 1.00 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL31378278 | 1.00 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL16293722 | 1.00 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL15500967 | 1.00 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL16294102 | 1.00 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL25405291 | 1.00 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL16294490 | 1.00 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL16293721 | 1.00 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL10774158 | 0.98 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774035-B2 | Preparation of amino acids and amino acid derivatives | UMICORE AG & CO. KG (DE) | 2020-09-15 | — | — | US | disclosed |
| US-20190276388-A1 | PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES | UMICORE AG & CO KG (DE) | 2019-09-12 | — | — | US | disclosed |
| EP-3515885-A1 | PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES | UMICORE AG & CO. KG (DE) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018057290-A1 | PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES | MATERIA, INC. (US) | 2018-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276388-A1 | PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES | AADAT, BCAT1, BCAT2 | HCAR2 1493/4885KEAP1 2075/4885NFE2L2 591/4885 |
| US-10774035-B2 | Preparation of amino acids and amino acid derivatives | AADAT, BCAT1, BCAT2 | HCAR2 1493/4885KEAP1 2075/4885NFE2L2 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.